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What does tacrolimus level mean? The tacrolimus test is used to measure the amount of the drug in the blood to determine whether the concentration has reached a therapeutic level and is below the toxic level. Tacrolimus can cause kidney damage (nephrotoxicity), especially in high doses.
How does tacrolimus ointment work? Tacrolimus ointment works on the immune system and directly on skin cells. This resulting drug-protein complex inhibits calcineurin (a calcium-dependent phosphatase transmitting chemical) that in turn reduces the activity of T-lymphocytes in the immune system.
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